The ninth season premiered on December 1, 2009, and on May 14, 2010, ABC officially cancelled the series. The new title sequences features the four new characters–Denise, Lucy, Drew, and Cole, as well as Dr. Janae Bakken and Debra Fordham were writers and producers during the first eight seasons, each writing 16 episodes.
The new main cast included Eliza Coupe returning to the recurring role of Denise "Jo" Mahoney from season eight, Dave Franco as Cole, a charming, confidently stupid, and incredibly entitled medical student whose family donated the money to build the school, Production for the final season took place at Culver Studios.
On May 14, 2010, it was officially announced that the show was canceled.
In the season eight finale "My Finale", the "real J.
D.", Jonathan Doris, made a cameo appearance as the doctor who said "adios" to J. In the show, Sacred Heart is an inner-city teaching hospital located in California.
Mc Ginley and Faison were joined by "a quartet of newbies (most of them playing students)" as full-time regulars, while one of the freshmen "will be fairly famous".